Quercetin and Zinc for Immune Support
Looking to supercharge your immune system? Quercetin and zinc, when combined, create a powerful synergy that can significantly enhance your body’s natural defenses.
While both quercetin and zinc offer individual immune-boosting benefits, their combined effect is truly remarkable. Quercetin acts as an “ionophore” for zinc, essentially shuttling it into your cells for enhanced immune activity.
Let’s explore the benefits of quercetin and zinc for immune support and how you can harness their power to stay healthy.

Zinc: The Immune System's Messenger
Zinc is an essential mineral that plays a vital role in immune function:
Quercetin: The Antiviral Powerhouse
Quercetin is a flavonoid (a type of plant pigment) with potent antiviral properties:
The Synergistic Power of Quercetin and Zinc
The combination of quercetin and zinc for immune support creates a dynamic duo that amplifies their individual benefits.
- Zinc Ionophore: Quercetin acts as an ionophore for zinc, meaning it binds to zinc and transports it into cells, where it can exert its immune-boosting effects [4].
- Enhanced Antiviral Activity: Since the COVID-19 pandemic, researchers have highlighted the potential of quercetin and zinc in combination. Studies suggest that this combination can inhibit the replication of viruses, including COVID-19 [5]. It’s believed to have similar effects against other respiratory infections.
Boosting Your Quercetin and Zinc Levels
Both quercetin and zinc are found naturally in various foods:
- Quercetin-Rich Foods: Apples, grapes, citrus fruits, cherries, blueberries, broccoli, tomatoes, kale, green tea, coffee, and onions.
- Zinc-Rich Foods: Legumes, nuts, meats, shellfish, milk and dairy products, eggs, grains, and potatoes.
While it’s possible to obtain quercetin and zinc through your diet, supplementation can be beneficial, especially during times of increased need, such as during cold and flu season or when your diet is lacking.
Quercetin and Zinc Supplements
You can find quercetin and zinc supplements individually or in combination formulas.
- Quercetin Dosage: Look for a supplement that provides 500-1000mg per day [6][7].
- Zinc Dosage: The recommended daily intake for zinc is 8-12mg. You can increase this dosage during illness.
The Benefits of Quercetin and Zinc for Immune Health
Quercetin and zinc for immune support offer a range of benefits:
- Immune Boosting: They enhance immune cell activity and response.
- Antioxidant Protection: They protect cells from damage caused by free radicals.
- Anti-inflammatory Action: They help reduce inflammation throughout the body.
- Infection Prevention and Recovery: They can help prevent infections and support faster recovery.
By incorporating quercetin and zinc for immune support into your wellness routine, you can give your immune system a powerful boost and enhance your overall health.
Cites and Sources
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[1] - Read, S. A., Obeid, S., Ahlenstiel, C., & Ahlenstiel, G. (2019). The role of zinc in antiviral immunity. Advances in Nutrition, 10(4), 696–710. https://doi.org/10.1093/advances/nmz013
[2] - Prasad, A. S. (2009). Zinc: role in immunity, oxidative stress and chronic inflammation. Current Opinion in Clinical Nutrition & Metabolic Care, 12(6), 646–652. https://doi.org/10.1097/mco.0b013e3283312956
[3] - ClinicalTrials.gov. (n.d.). https://clinicaltrials.gov/study/NCT04468139
[4] - Dabbagh-Bazarbachi, H., Clergeaud, G., Quesada, I. M., Ortiz, M., O'Sullivan, C. K., & Fernández-Larrea, J. B. (2014). Zinc ionophore activity of quercetin and epigallocatechin-gallate: from Hepa 1-6 cells to a liposome model. Journal of agricultural and food chemistry, 62(32), 8085–8093. https://doi.org/10.1021/jf5014633
[5] - Velthuis, A. J. W. T., Van Den Worm, S. H. E., Sims, A. C., Baric, R. S., Snijder, E. J., & Van Hemert, M. J. (2010). ZN2+ inhibits coronavirus and arterivirus RNA polymerase activity in vitro and zinc ionophores block the replication of these viruses in cell culture. PLoS Pathogens, 6(11), e1001176. https://doi.org/10.1371/journal.ppat.1001176
[6] - Jin, F., Nieman, D. C., Shanely, R. A., Knab, A. M., Austin, M. D., & Sha, W. (2010). The variable plasma quercetin response to 12-week quercetin supplementation in humans. European Journal of Clinical Nutrition, 64(7), 692–697. https://doi.org/10.1038/ejcn.2010.91
[7] - Knab, A. M., Shanely, R. A., Henson, D. A., Jin, F., Heinz, S. A., Austin, M. D., & Nieman, D. C. (2011). Influence of quercetin supplementation on disease risk factors in Community-Dwelling Adults. Journal of the American Dietetic Association, 111(4), 542–549. https://doi.org/10.1016/j.jada.2011.01.013